The unique and often hilarious bond between sisters and brothers is explored in this comedy about four different sets of siblings. Rory always wanted to be famous, and isn’t happy that his brother beat him to it. Sarah is shocked to discover she has an Indian half-sister, the result of her mom’s promiscuous year in a cult. Nikki and Maggie go on a road trip with a loser who is making their reconciliation difficult, and Louise is trying to figure out if her brother is mentally ill or just a jerk. But finding the answers without losing your mind is never easy when it comes to family.